Tofogliflozin Salt Cocrystals with Sodium Acetate and Potassium Acetate
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منابع مشابه
Salt-Loaded Deoxycorticosterone Acetate-Escaped Rats
A B S T R A C T Proximal and distal tubular function was compared with urinary excretion in rats after chronic administration of salt and deoxycorticosterone acetate (DOCA) or during salt deprivation. DOCA rats excreted significantly more sodium than did salt-deprived rats. Measurements of tubular fluid to plasma (TF/P) inulin ratios and concentrations of sodium and potassium in quantitative, t...
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To evaluate the effect of chronic hyperinsulinemia on blood pressure in salt-dependent hypertension, we infused insulin (1.0 IU/d, n = 15) or saline (n = 13) for 4 weeks into deoxycorticosterone acetate-salt hypertensive rats. The insulin infusion increased plasma insulin levels to 24 +/- 2 microU/mL, which was higher than in the saline-infused rats (9 +/- 1 microU/mL) but was still within the ...
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The crystal structure of the title compound, K(+)·C(3)H(4)NO(4) (-)·H(2)O, consists of potassium cations, monoanions of 2-carboxy-acetohydroxamic acid [namely 2-(N-hydroxy-carbamo-yl)acetate] and solvent water mol-ecules. The elements of the structure are united in a three-dimensional network by numerous K⋯O coordinate bonds and O-H⋯O and N-H⋯O hydrogen bonds. The coordination sphere of the K(+...
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The Na+-K+ pump activity was determined in femoral arterial smooth muscle from deoxycorticosterone acetate (DOCA)-salt hypertensive rats using potassium relaxation and ouabain-sensitive 86Rb uptake as indices. The membrane-stabilizing effect of calcium and its relation to Na+-K+ pump activity also were examined. Femoral arteries from DOCA-salt rats exhibited a greater relaxation in response to ...
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Hyperkalaemia is a common, significant electrolyte disorder in uremia. Patients with chronic renal failure (CRF) undergoing haemodialysis (HD) accumulate potassium during the interdialysis period, and clearance of this potassium is one of the functions of haemodialysis. A sudden decrease in blood potassium levels during haemodialysis can induce or worsen arrhythmias, (Cupisti et al., 1999) part...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 2018
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.c18-00483